Anti-Inflammatory

Inflammatory conditions are a major source of pain, including arthritis, colitis and other similar conditions. Colostrum has anti-inflammatory activity which can reduce inflammation, thus helping reduce the pain due to these conditions.

• Colostrum has anti-inflammatory activity^83,84
• Tumor necrosis factor-alpha (TNF-α) receptors in colostrum bind TNF-α, a cytokine which controls the inflammatory cytokine cascade, effectively turning off inflammation at its source^85,86
• Colostrum also contains interleukin-1ra (IL-1ra), the IL-1 receptor protein, which also acts to inactivate the inflammatory activity of IL-1⁸⁷
• Colostrum has been shown to be beneficial to chronic inflammatory diseases, such as various forms of arthritis and Crohn’s disease, which have been linked to gut inflammation^88-90
• Lactoferrin has strong antioxidant characteristics which take place by two separate mechanisms: binding catalytic iron generated during cell destruction; and binding bacterial lipopolysaccharide (LPS) which causes a decrease in LPS bioactivity, such as increasing neutrophil O2 production⁹¹
• Lactoferrin also inhibits the production of inflammatory cytokines⁹²
• colostrinin^® (PRP) also acts as an oxidative stress regulator⁹³